Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

CB2R/FAAH modulator-3

🥰Excellent
Catalog No. T67747Cas No. 2876918-67-9

CB2R/FAAH modulator-3 (compound 27) is a modulator targeting CB2R and FAAH, acting as a CB2R agonist with a Ki value of 20.1 nM and a CB1R agonist with a Ki value of 67.6 nM, while inhibiting FAAH with an IC50 value of 3.4 μM. This compound has research value in cancer, neurodegenerative disease-related inflammatory cascades, and COVID-19 infection.

CB2R/FAAH modulator-3

CB2R/FAAH modulator-3

🥰Excellent
Purity: 99.81%
Catalog No. T67747Cas No. 2876918-67-9
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting CB2R and FAAH, acting as a CB2R agonist with a Ki value of 20.1 nM and a CB1R agonist with a Ki value of 67.6 nM, while inhibiting FAAH with an IC50 value of 3.4 μM. This compound has research value in cancer, neurodegenerative disease-related inflammatory cascades, and COVID-19 infection.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$31In StockIn Stock
10 mg$53In StockIn Stock
25 mg$108In StockIn Stock
50 mg$163In StockIn Stock
100 mg$247In StockIn Stock
1 mL x 10 mM (in DMSO)$35In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.81%
Contact us for more batch information

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity
Description
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting CB2R and FAAH, acting as a CB2R agonist with a Ki value of 20.1 nM and a CB1R agonist with a Ki value of 67.6 nM, while inhibiting FAAH with an IC50 value of 3.4 μM. This compound has research value in cancer, neurodegenerative disease-related inflammatory cascades, and COVID-19 infection.
Targets&IC50
CB2:20.1 nM (Ki), CB1:67.6 nM (Ki)
In vitro
CB2R/FAAH modulator-3 (compound 27) at 10 μM reduces production of the inflammatory cytokines TNFα, IFN-γ, IL-1β, and IL-6 in unstimulated monocytes and macrophages[1].
Chemical Properties
Molecular Weight341.49
FormulaC22H31NO2
Cas No.2876918-67-9
SmilesCCCCCOc1ccccc1C(=O)NC12CC3CC(CC(C3)C1)C2
Relative Density.1.10 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (146.42 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9283 mL14.6417 mL29.2834 mL146.4172 mL
5 mM0.5857 mL2.9283 mL5.8567 mL29.2834 mL
10 mM0.2928 mL1.4642 mL2.9283 mL14.6417 mL
20 mM0.1464 mL0.7321 mL1.4642 mL7.3209 mL
50 mM0.0586 mL0.2928 mL0.5857 mL2.9283 mL
100 mM0.0293 mL0.1464 mL0.2928 mL1.4642 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

FAAHCB2R/FAAHmodulator3CB2R/FAAH modulator-3CB2RCannabinoidReceptorCannabinoid Receptor
Related Tags: buy CB2R/FAAH modulator-3 | purchase CB2R/FAAH modulator-3 | CB2R/FAAH modulator-3 cost | order CB2R/FAAH modulator-3 | CB2R/FAAH modulator-3 chemical structure | CB2R/FAAH modulator-3 in vitro | CB2R/FAAH modulator-3 formula | CB2R/FAAH modulator-3 molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.