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Triazavirin

🥰Excellent
Catalog No. T8354Cas No. 928659-17-0

Triazavirin, a nucleoside analogue of nucleic acid, is an antiviral agent.

Triazavirin
Other Forms of Triazavirin:
RiamilovirT8904123606-06-4
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Triazavirin

🥰Excellent
Purity: 99.55%
Catalog No. T8354Cas No. 928659-17-0
Triazavirin, a nucleoside analogue of nucleic acid, is an antiviral agent.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$33In StockIn Stock
10 mg$53In StockIn Stock
25 mg$94In StockIn Stock
50 mg$153In StockIn Stock
100 mg$227In StockIn Stock
200 mg$337In StockIn Stock
1 mL x 10 mM (in DMSO)$35In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.55%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Triazavirin, a nucleoside analogue of nucleic acid, is an antiviral agent.
In vivo
In high doses (200-400 mg/kg) Triazavirin moderately protected the infected animals.?A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically (p ≤ 0.05) valid decrease of the virus accumulation in the target organ (the brain) were observed[1].
Chemical Properties
Molecular Weight286.2
FormulaC5H7N6NaO5S
Cas No.928659-17-0
SmilesO.O.[Na+].CSc1nc2[n-]nc([N+]([O-])=O)c(=O)n2n1
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 125 mg/mL (436.76 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (13.98 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4941 mL17.4703 mL34.9406 mL174.7030 mL
5 mM0.6988 mL3.4941 mL6.9881 mL34.9406 mL
10 mM0.3494 mL1.7470 mL3.4941 mL17.4703 mL
20 mM0.1747 mL0.8735 mL1.7470 mL8.7352 mL
50 mM0.0699 mL0.3494 mL0.6988 mL3.4941 mL
100 mM0.0349 mL0.1747 mL0.3494 mL1.7470 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TriazavirintransmissionTick-bornRNASynthesisRNA SynthesisRNAreplicationNucleosideAntimetaboliteNucleoside Antimetabolite/AnalogNucleoside AntimetaboliteNucleoside AnaloguenucleosideInhibitorinhibitInfluenzaVirusInfluenza VirusInfluenza virusinfluenzaencephalitisDNASynthesisDNA/RNA SynthesisDNA SynthesisDNAantiviralAnalog
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