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Triazavirin

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Catalog No. T8354Cas No. 928659-17-0

Triazavirin, a nucleoside analogue of nucleic acid, is an antiviral agent.

Triazavirin

Triazavirin

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🥰Excellent
Purity: 99.55%
Catalog No. T8354Cas No. 928659-17-0
Triazavirin, a nucleoside analogue of nucleic acid, is an antiviral agent.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$33In StockIn Stock
10 mg$53In StockIn Stock
25 mg$94In StockIn Stock
50 mg$153In StockIn Stock
100 mg$227In StockIn Stock
200 mg$337In StockIn Stock
1 mL x 10 mM (in DMSO)$35In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.55%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Triazavirin, a nucleoside analogue of nucleic acid, is an antiviral agent.
In vivo
In high doses (200-400 mg/kg) Triazavirin moderately protected the infected animals.?A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically (p ≤ 0.05) valid decrease of the virus accumulation in the target organ (the brain) were observed[1].
Chemical Properties
Molecular Weight286.2
FormulaC5H7N6NaO5S
Cas No.928659-17-0
SmilesO.O.[Na+].CSc1nc2[n-]nc([N+]([O-])=O)c(=O)n2n1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 125 mg/mL (436.76 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (13.98 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4941 mL17.4703 mL34.9406 mL174.7030 mL
5 mM0.6988 mL3.4941 mL6.9881 mL34.9406 mL
10 mM0.3494 mL1.7470 mL3.4941 mL17.4703 mL
20 mM0.1747 mL0.8735 mL1.7470 mL8.7352 mL
50 mM0.0699 mL0.3494 mL0.6988 mL3.4941 mL
100 mM0.0349 mL0.1747 mL0.3494 mL1.7470 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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