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(Rac)-BRD0705

Name: (Rac)-BRD0705
Brand: TargetMol
SKU: T12664
Price: 88 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12664Cas No. 1597440-03-3

(Rac)-BRD0705, the less active racemate of BRD0705, is an effective and selective inhibitor of GSK3α.

(Rac)-BRD0705

🥰Excellent

Purity: 99.7%

Catalog No. T12664Cas No. 1597440-03-3

(Rac)-BRD0705, the less active racemate of BRD0705, is an effective and selective inhibitor of GSK3α.

Pack Size	Price	Availability
1 mg	$88	In Stock
5 mg	$223	In Stock
10 mg	$333	In Stock
25 mg	$537	In Stock
50 mg	$732	In Stock
100 mg	$990	In Stock
1 mL x 10 mM (in DMSO)	$157	In Stock

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Batch Information

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Purity:99.7%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

(Rac)-BRD0705, the less active racemate of BRD0705, is an effective and selective inhibitor of GSK3α.

Chemical Properties

Molecular Weight	321.42
Formula	C₂₀H₂₃N₃O
Cas No.	1597440-03-3
Smiles	C(C)C1(C2=C(NC=3C1=CNN3)CC(C)(C)CC2=O)C4=CC=CC=C4
Relative Density.	1.22 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 245 mg/mL (762.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1112 mL	15.5560 mL	31.1119 mL	155.5597 mL
5 mM	0.6222 mL	3.1112 mL	6.2224 mL	31.1119 mL
10 mM	0.3111 mL	1.5556 mL	3.1112 mL	15.5560 mL
20 mM	0.1556 mL	0.7778 mL	1.5556 mL	7.7780 mL
50 mM	0.0622 mL	0.3111 mL	0.6222 mL	3.1112 mL
100 mM	0.0311 mL	0.1556 mL	0.3111 mL	1.5556 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc