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KRAS G12D inhibitor 26

Name: KRAS G12D inhibitor 26
Brand: TargetMol
SKU: T205666
Price: 603 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T205666Cas No. 2972625-49-1

KRAS G12D inhibitor 26 (Compound 64B) is an inhibitor of KRAS G12D with an IC50 ≤ 100 nM.

KRAS G12D inhibitor 26

🥰Excellent

Purity: 99.93%

Catalog No. T205666Cas No. 2972625-49-1

KRAS G12D inhibitor 26 (Compound 64B) is an inhibitor of KRAS G12D with an IC50 ≤ 100 nM.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$603	-	In Stock
5 mg	$1,260	-	In Stock
10 mg	$1,720	-	In Stock
25 mg	$2,870	-	In Stock
50 mg	$3,850	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.93%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

KRAS G12D inhibitor 26 (Compound 64B) is an inhibitor of KRAS G12D with an IC50 ≤ 100 nM.

Chemical Properties

Molecular Weight	663.23
Formula	C₃₅H₄₄ClFN₈O₂
Cas No.	2972625-49-1
Smiles	CN1[C@]2(C=3C(CCC2)=CC=CC3)CC=4C(C1)=C(N=C(OC[C@@]56N(C[C@H](F)C5)CCC6)N4)N7CC=8N(CCC7)N=C(C(N(C)C)=O)C8Cl
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80.00 mg/mL (120.62 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5078 mL	7.5389 mL	15.0777 mL	75.3886 mL
5 mM	0.3016 mL	1.5078 mL	3.0155 mL	15.0777 mL
10 mM	0.1508 mL	0.7539 mL	1.5078 mL	7.5389 mL
20 mM	0.0754 mL	0.3769 mL	0.7539 mL	3.7694 mL
50 mM	0.0302 mL	0.1508 mL	0.3016 mL	1.5078 mL
100 mM	0.0151 mL	0.0754 mL	0.1508 mL	0.7539 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc