Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

CAY10669

Name: CAY10669
Brand: TargetMol
SKU: T35818
Rating: 4.5 (1 reviews)

Copy Product Info

😃Good

Catalog No. T35818Cas No. 1243583-88-1

CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM), displaying a 2-fold improvement in inhibitory potency over anacardic acid . At 30-60 μM, CAY10669 can dose-dependently inhibit histone H4 acetylation in HepG2 cells in vitro.

CAY10669

Copy Product Info

😃Good

Catalog No. T35818Cas No. 1243583-88-1

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$287	35 days	35 days
5 mg	$1,290	35 days	35 days
10 mg	$2,290	35 days	35 days

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Resource Download

Product Introduction

Bioactivity

Description	CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM), displaying a 2-fold improvement in inhibitory potency over anacardic acid . At 30-60 μM, CAY10669 can dose-dependently inhibit histone H4 acetylation in HepG2 cells in vitro.
Targets&IC50	PCAF:662 μM

Chemical Properties

Molecular Weight	326.39
Formula	C₂₀H₂₂O₄
Cas No.	1243583-88-1
Smiles	C(O)(=O)C1=C(/C=C\C2=CC=C(OCCCCC)C=C2)C=CC=C1O
Relative Density.	1.192 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (91.91 mM), Sonication is recommended.

Ethanol: 30 mg/mL (91.91 mM), Sonication is recommended.

DMF: 30 mg/mL (91.91 mM), Sonication is recommended.

Solution Preparation Table

DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
1 mM	3.0638 mL	15.3191 mL	30.6382 mL	153.1910 mL
5 mM	0.6128 mL	3.0638 mL	6.1276 mL	30.6382 mL
10 mM	0.3064 mL	1.5319 mL	3.0638 mL	15.3191 mL
20 mM	0.1532 mL	0.7660 mL	1.5319 mL	7.6595 mL
50 mM	0.0613 mL	0.3064 mL	0.6128 mL	3.0638 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc