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RU 24969 free base

Name: RU 24969 free base
Brand: TargetMol
SKU: T8593
Price: 56 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T8593Cas No. 66611-26-5

Alias 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.

RU 24969 free base

🥰Excellent

Purity: 97.38%

Catalog No. T8593Alias 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleCas No. 66611-26-5

RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.

Pack Size	Price	Availability
5 mg	$56	In Stock
10 mg	$85	In Stock
50 mg	$276	In Stock
100 mg	$412	In Stock
1 mL x 10 mM (in DMSO)	$66	In Stock

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Batch Information

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Purity:97.38%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.
Targets&IC50	5-HT1B receptor:0.38 nM (Ki), 5-HT1A receptor:2.5 nM (Ki)
Synonyms	5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Chemical Properties

Molecular Weight	228.29
Formula	C₁₄H₁₆N₂O
Cas No.	66611-26-5
Smiles	COC1=CC2=C(NC=C2C2=CCNCC2)C=C1
Relative Density.	1.174 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (131.41 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3804 mL	21.9020 mL	43.8039 mL	219.0197 mL
5 mM	0.8761 mL	4.3804 mL	8.7608 mL	43.8039 mL
10 mM	0.4380 mL	2.1902 mL	4.3804 mL	21.9020 mL
20 mM	0.2190 mL	1.0951 mL	2.1902 mL	10.9510 mL
50 mM	0.0876 mL	0.4380 mL	0.8761 mL	4.3804 mL
100 mM	0.0438 mL	0.2190 mL	0.4380 mL	2.1902 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc