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Bacitracin Zinc

Name: Bacitracin Zinc
Brand: TargetMol
SKU: T2208
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2208Cas No. 1405-89-6

Alias Zinc bacitracin, Bacitracin zinc salt

Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=10 μM).

Bacitracin Zinc

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Catalog No. T2208Alias Zinc bacitracin, Bacitracin zinc saltCas No. 1405-89-6

Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=10 μM).

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$36	In Stock	In Stock
500 mg	$56	In Stock	-
1 g	$81	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Appearance:Solid

Color:White

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COA HNMR MS

Product Introduction

Bacitracin Zinc AI Summary

Bacitracin Zinc exhibits antibacterial activity against various strains of Staphylococcus aureus, including methicillin-resistant strains, as well as Staphylococcus epidermidis and Enterococcus species. The compound demonstrates a minimal inhibitory concentration (MIC95) of 15.62 µM or 31.25 µM for these bacterial strains when incubated for 24 or 48 hours under dark conditions. However, it does not show significant antibacterial activity against Escherichia coli, with an MIC95 greater than 500.0 µM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=10 μM).
Targets&IC50	MET:10 μM
Synonyms	Zinc bacitracin, Bacitracin zinc salt

Chemical Properties

Molecular Weight	1486.07
Formula	C₆₆H₁₀₁N₁₇O₁₆SZn
Cas No.	1405-89-6
Smiles	[Zn++].CCC(C)C(N)C1=NCC(S1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC([O-])=O)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC1=O)[C@@H](C)CC
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (67.29 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.6729 mL	3.3646 mL	6.7292 mL	33.6458 mL
5 mM	0.1346 mL	0.6729 mL	1.3458 mL	6.7292 mL
10 mM	0.0673 mL	0.3365 mL	0.6729 mL	3.3646 mL
20 mM	0.0336 mL	0.1682 mL	0.3365 mL	1.6823 mL
50 mM	0.0135 mL	0.0673 mL	0.1346 mL	0.6729 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc