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SIRT6-IN-5(SIRT6 inhibitor 5) is a potent and selective SIRT6 inhibitor with an IC50 value of 34 μM.SIRT6-IN-5 is immunosuppressive and chemo-sensitizing, increases H3K9 acetylation and glucose uptake in cultured cells, and reduces T-cell proliferation.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $51 | In Stock | |
| 5 mg | $122 | In Stock | |
| 10 mg | $197 | In Stock | |
| 25 mg | $397 | In Stock | |
| 50 mg | $788 | In Stock | |
| 100 mg | $1,070 | In Stock | |
| 500 mg | $2,130 | In Stock |
| Description | SIRT6-IN-5(SIRT6 inhibitor 5) is a potent and selective SIRT6 inhibitor with an IC50 value of 34 μM.SIRT6-IN-5 is immunosuppressive and chemo-sensitizing, increases H3K9 acetylation and glucose uptake in cultured cells, and reduces T-cell proliferation. |
| Targets&IC50 | SIRT6:34 μM |
| Synonyms | SIRT6 inhibitor-5, SIRT6 inhibitor5, SIRT6 inhibitor 5, SIRT6 IN 5 |
| Molecular Weight | 366.32 |
| Formula | C19H14N2O6 |
| Cas No. | 891002-11-2 |
| Smiles | N(C(=O)C1=CC=C(NC(=O)C2=CC=CO2)C=C1)C3=CC(C(O)=O)=C(O)C=C3 |
| Relative Density. | 1.520 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (150.14 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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