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VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $37 | In Stock | In Stock | |
| 50 mg | $56 | In Stock | In Stock | |
| 100 mg | $83 | In Stock | In Stock | |
| 200 mg | $125 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock | In Stock |
| Description | VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent. |
| Targets&IC50 | M1:3.1 μM(EC50) |
| In vivo | VU0119498 treatment of wild-type mice caused a significant increase in plasma insulin levels, accompanied by a striking improvement in glucose tolerance |
| Molecular Weight | 316.15 |
| Formula | C15H10BrNO2 |
| Cas No. | 79183-37-2 |
| Smiles | Brc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1 |
| Relative Density. | 1.604 g/cm3 (Predicted) |
| Color | Red |
| Appearance | Solid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 15 mg/mL (47.45 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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