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Isosorbide

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Catalog No. T6551Cas No. 652-67-5
Alias Isobide, Hydronol, D-Isosorbide, Dianhydro-D-glucitol, Devicoran

Isosorbide (Devicoran) is a heterocyclic compound that is derived from glucose, used as a diuretic.

Isosorbide
Other Forms of Isosorbide:

Isosorbide

🥰Excellent
Purity: 97.28%
Catalog No. T6551Alias Isobide, Hydronol, D-Isosorbide, Dianhydro-D-glucitol, DevicoranCas No. 652-67-5
Isosorbide (Devicoran) is a heterocyclic compound that is derived from glucose, used as a diuretic.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 g$29-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.28%
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Product Introduction

Bioactivity
Description
Isosorbide (Devicoran) is a heterocyclic compound that is derived from glucose, used as a diuretic.
In vitro
Isosorbide increases urine volume by increasing the amount of osmotically active solute in the urine. Osmotic diuretics also increase the osmolarity of plasma. Isosorbide is used to prevent or treat chest pain (angina). It works by relaxing the blood vessels to the heart, so the blood and oxygen supply to the heart is increased. [1]
SynonymsIsobide, Hydronol, D-Isosorbide, Dianhydro-D-glucitol, Devicoran
Chemical Properties
Molecular Weight146.14
FormulaC6H10O4
Cas No.652-67-5
SmilesO[C@@H]1[C@@]2([C@@]([C@H](O)CO2)(OC1)[H])[H]
Relative Density.1.0945 g/cm3 (Estimated)
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (342.14 mM), Sonication is recommended.
H2O: 100 mg/mL (684.28 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (13.69 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM6.8428 mL34.2138 mL68.4275 mL342.1377 mL
5 mM1.3686 mL6.8428 mL13.6855 mL68.4275 mL
10 mM0.6843 mL3.4214 mL6.8428 mL34.2138 mL
20 mM0.3421 mL1.7107 mL3.4214 mL17.1069 mL
50 mM0.1369 mL0.6843 mL1.3686 mL6.8428 mL
100 mM0.0684 mL0.3421 mL0.6843 mL3.4214 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

vasodilatingpainIsosorbideInhibitorinhibithyperosmoticheartfailurediureticchestangina
Related Tags: buy Isosorbide | purchase Isosorbide | Isosorbide cost | order Isosorbide | Isosorbide chemical structure | Isosorbide in vitro | Isosorbide formula | Isosorbide molecular weight
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