Shopping Cart

Remove All
Your shopping cart is currently empty

DDR Inhibitor

Name: DDR Inhibitor
Brand: TargetMol
SKU: T10985
Price: 118 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10985Cas No. 1644069-80-6

DDR inhibitor is a potent discidin domain receptor (DDR) inhibitor. The IC50 of DDR2 is 3.3 nM, and DDR1 has 53% inhibition at 1.5 nM.

DDR Inhibitor

🥰Excellent

Purity: 99.61%

Catalog No. T10985Cas No. 1644069-80-6

DDR inhibitor is a potent discidin domain receptor (DDR) inhibitor. The IC50 of DDR2 is 3.3 nM, and DDR1 has 53% inhibition at 1.5 nM.

Pack Size	Price	Availability
1 mg	$118	In Stock
5 mg	$247	In Stock
10 mg	$397	In Stock
25 mg	$798	In Stock
50 mg	$1,270	In Stock
100 mg	$1,720	In Stock
1 mL x 10 mM (in DMSO)	$273	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

Questions

Batch Information

Select Batch

Purity:99.61%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	DDR inhibitor is a potent discidin domain receptor (DDR) inhibitor. The IC50 of DDR2 is 3.3 nM, and DDR1 has 53% inhibition at 1.5 nM.
Targets&IC50	DDR2:3.3 nM , DDR1:1.5 nM (IC53)
In vitro	DDR inhibitor is an effective DDR inhibitor. The IC50 of DDR2 is 3.3 nM, which has 53% inhibition on DDR1 at 1.5 nM.

Chemical Properties

Molecular Weight	417.44
Formula	C₂₃H₂₀FN₅O₂
Cas No.	1644069-80-6
Smiles	Cc1ccc(CNC(=O)Nc2cccc(F)c2)cc1NC(=O)c1cnc2ccccn12
Relative Density.	1.32 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (119.78 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.79 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3956 mL	11.9778 mL	23.9555 mL	119.7777 mL
5 mM	0.4791 mL	2.3956 mL	4.7911 mL	23.9555 mL
10 mM	0.2396 mL	1.1978 mL	2.3956 mL	11.9778 mL
20 mM	0.1198 mL	0.5989 mL	1.1978 mL	5.9889 mL
50 mM	0.0479 mL	0.2396 mL	0.4791 mL	2.3956 mL
100 mM	0.0240 mL	0.1198 mL	0.2396 mL	1.1978 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc