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Tetraethylammonium chloride

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Catalog No. T7538Cas No. 56-34-8

Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transporter proteins and has antitumor properties.

Tetraethylammonium chloride
Other Forms of Tetraethylammonium chloride:

Tetraethylammonium chloride

🥰Excellent
Catalog No. T7538Cas No. 56-34-8
Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transporter proteins and has antitumor properties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 g$34-In Stock
5 g$44-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:≥95%
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COA HNMR

Product Introduction

Bioactivity
Description
Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transporter proteins and has antitumor properties.
In vitro
Ex vivo guinea pig airway rings, human ASM strips and small peripheral airways in rat lungs slices relaxed in response to niflumic acid following depolarization-induced contraction induced by K(+) channel blockade with tetraethylammonium chloride (TEA).?In isolated human airway smooth muscle cells TEA induce depolarization as measured by a fluorescent indicator or whole cell patch clamp and this depolarization was reversed by niflumic acid[1].
Chemical Properties
Molecular Weight165.7
FormulaC8H20ClN
Cas No.56-34-8
Smiles[Cl-].CC[N+](CC)(CC)CC
Relative Density.1.08 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 32.5 mg/mL (196.14 mM), Sonication is recommended.
H2O: 100 mg/mL (603.50 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (12.07 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM6.0350 mL30.1750 mL60.3500 mL301.7502 mL
5 mM1.2070 mL6.0350 mL12.0700 mL60.3500 mL
10 mM0.6035 mL3.0175 mL6.0350 mL30.1750 mL
20 mM0.3018 mL1.5088 mL3.0175 mL15.0875 mL
50 mM0.1207 mL0.6035 mL1.2070 mL6.0350 mL
100 mM0.0604 mL0.3018 mL0.6035 mL3.0175 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Keywords

Tetraethylammonium chlorideTetraethylammonium ChlorideTetraethylammoniumROSPotassiumChannelPotassium Channelnon-selectiveKcsAInhibitorinhibitcontractilityBcl-2Baxantitumorantiproliferative
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