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uk-50001

Name: uk-50001
Brand: TargetMol
SKU: T67815
Price: 162 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T67815Cas No. 857900-47-1

uk-50001 is a phosphodiesterase (PDE) 4 inhibitor that can be used for many diseases, especially inflammation, allergies, respiratory diseases, disorders and conditions and wounds.

uk-50001

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Purity: 99.90%

Catalog No. T67815Cas No. 857900-47-1

uk-50001 is a phosphodiesterase (PDE) 4 inhibitor that can be used for many diseases, especially inflammation, allergies, respiratory diseases, disorders and conditions and wounds.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$162	In Stock	In Stock
5 mg	$400	In Stock	In Stock
10 mg	$600	In Stock	In Stock
25 mg	$959	In Stock	In Stock
50 mg	$1,280	In Stock	In Stock
100 mg	$1,750	In Stock	In Stock
500 mg	$3,490	-	In Stock
1 mL x 10 mM (in DMSO)	$495	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.90%

Appearance:Solid

Color:White

Resource Download

COA FNMR HNMR LCMS

Product Introduction

Bioactivity

Description

uk-50001 is a phosphodiesterase (PDE) 4 inhibitor that can be used for many diseases, especially inflammation, allergies, respiratory diseases, disorders and conditions and wounds.

Chemical Properties

Molecular Weight	499.48
Formula	C₂₆H₂₄F₃N₃O₄
Cas No.	857900-47-1
Smiles	O(C1=C(C(NC2CCC(NC(=O)C3=C(O)C=CC(C)=C3)CC2)=O)C=C(F)C=N1)C4=CC(F)=C(F)C=C4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (55.06 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0021 mL	10.0104 mL	20.0208 mL	100.1041 mL
5 mM	0.4004 mL	2.0021 mL	4.0042 mL	20.0208 mL
10 mM	0.2002 mL	1.0010 mL	2.0021 mL	10.0104 mL
20 mM	0.1001 mL	0.5005 mL	1.0010 mL	5.0052 mL
50 mM	0.0400 mL	0.2002 mL	0.4004 mL	2.0021 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc