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N-Acetyl-L-glutamic acid

N-Acetyl-L-glutamic acid
N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phosphate synthetase in the urea cycle. A deficiency in N-acetyl glutamate synthase or a genetic mutation in the gene coding for the enzyme will lead to urea cycle failure in which ammonia is not converted to urea, but rather accumulated in the blood leading to the condition called Type I hyperammonemia.
Catalog No. T5267Cas No. 1188-37-0
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Purity:99.67%
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N-Acetyl-L-glutamic acid

Purity: 99.67%
Catalog No. T5267Alias N-Acetylglutamic acid, Ac-L-Glu-OHCas No. 1188-37-0

N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phosphate synthetase in the urea cycle. A deficiency in N-acetyl glutamate synthase or a genetic mutation in the gene coding for the enzyme will lead to urea cycle failure in which ammonia is not converted to urea, but rather accumulated in the blood leading to the condition called Type I hyperammonemia.
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10 g$41In Stock
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Product Introduction

Bioactivity
Description
N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phosphate synthetase in the urea cycle. A deficiency in N-acetyl glutamate synthase or a genetic mutation in the gene coding for the enzyme will lead to urea cycle failure in which ammonia is not converted to urea, but rather accumulated in the blood leading to the condition called Type I hyperammonemia.
AliasN-Acetylglutamic acid, Ac-L-Glu-OH
Chemical Properties
Molecular Weight189.17
FormulaC7H11NO5
Cas No.1188-37-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (290.74 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.2863 mL26.4313 mL52.8625 mL264.3125 mL
5 mM1.0573 mL5.2863 mL10.5725 mL52.8625 mL
10 mM0.5286 mL2.6431 mL5.2863 mL26.4313 mL
20 mM0.2643 mL1.3216 mL2.6431 mL13.2156 mL
50 mM0.1057 mL0.5286 mL1.0573 mL5.2863 mL
100 mM0.0529 mL0.2643 mL0.5286 mL2.6431 mL

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