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3-Indoleacetic acid

Name: 3-Indoleacetic acid
Brand: TargetMol
SKU: T2O2791
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2O2791Cas No. 87-51-4

Alias indolylacetic acid, indoleacetic acid, Indole-3-acetic acid, IAA, 3-IAA, 1H-Indole-3-acetic acid

3-Indoleacetic acid (indolylacetic acid) (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.

3-Indoleacetic acid

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Purity: 99.85%

Catalog No. T2O2791Alias indolylacetic acid, indoleacetic acid, Indole-3-acetic acid, IAA, 3-IAA, 1H-Indole-3-acetic acidCas No. 87-51-4

3-Indoleacetic acid (indolylacetic acid) (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
500 mg	$41	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.85%

Appearance:Solid

Color:White to Yellow

Resource Download

COA HPLC HNMR LCMS

Product Introduction

3-Indoleacetic acid AI Summary

3-Indoleacetic acid demonstrates diverse biological activities and physicochemical properties. It has a rate constant for oxidation by HRP of 3.8 x 10^3 M^-1 s^-1 and exhibited notable cytotoxicity against V79 cells with a surviving fraction of 0.01. The compound does not significantly inhibit Arabidopsis thaliana mitochondrial PDF1A, PDF1B, or PDF2, with IC50 values greater than 1000000.0 nM. It exhibits poor permeability through artificial membranes (log P_app = -6.4) and has a log partition coefficient (log P) of 1.41, with a log Kow value of 1.42, indicating moderate hydrophobicity. 3-Indoleacetic acid binds to human serum albumin with a logKA of 0.102. Biologically, 3-Indoleacetic acid promotes growth in Oryza sativa, particularly at 125 ppm, and regulates root growth in cucumbers, showing greater than 150% activity at 10 mg/L. In enzyme inhibition, it affects CdpNPT and FtmPT1 in Aspergillus fumigatus with varied inhibition levels, and weakly antagonizes the human T1R2/T1R3 receptor (IC50 > 1000000.0 nM). It shows minimal inhibition of electric eel AChE (2.98%) and horse BChE (-7.42%). Moreover, 3-Indoleacetic acid has fungicidal activity against Cryphonectria parasitica, with inhibition zones increasing from 12.0 to 21.0 mm at higher concentrations and inhibits hyphal growth in other fungal species, demonstrating IC50 variation. It also promotes root formation in Vigna mungo cuttings and induces root growth in Fuchsia hybrida. As an antiviral, it inhibits HCV genotype 1a NS3 helicase (IC50 = 500,000.0 nM) and holds potential as an LOX inhibitor (IC50 = 42980.0 nM). Additionally, it weakly inhibits Streptococcus pyogenes SrtA mutant (8.6% inhibition at 100 uM) and activates transcription in yeast expressing AhR and ARNT (EC50 = 300,000.0 nM). These varied activities suggest that 3-Indoleacetic acid may serve diverse research and therapeutic applications..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	3-Indoleacetic acid (indolylacetic acid) (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.
Synonyms	indolylacetic acid, indoleacetic acid, Indole-3-acetic acid, IAA, 3-IAA, 1H-Indole-3-acetic acid

Chemical Properties

Molecular Weight	175.18
Formula	C₁₀H₉NO₂
Cas No.	87-51-4
Smiles	OC(CC1=CNC2=C1C=CC=C2)=O
Relative Density.	1.354 g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture,store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 262 mg/mL (1495.6 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (28.54 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.7084 mL	28.5421 mL	57.0841 mL	285.4207 mL
5 mM	1.1417 mL	5.7084 mL	11.4168 mL	57.0841 mL
10 mM	0.5708 mL	2.8542 mL	5.7084 mL	28.5421 mL
20 mM	0.2854 mL	1.4271 mL	2.8542 mL	14.2710 mL
50 mM	0.1142 mL	0.5708 mL	1.1417 mL	5.7084 mL
100 mM	0.0571 mL	0.2854 mL	0.5708 mL	2.8542 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc