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AT-130

🥰Excellent
Catalog No. T26674Cas No. 211364-06-6
Alias AT 130

AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging.

AT-130

AT-130

🥰Excellent
Purity: 97.81%
Catalog No. T26674Alias AT 130Cas No. 211364-06-6
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$35In StockIn Stock
5 mg$83In StockIn Stock
10 mg$133In StockIn Stock
25 mg$238In StockIn Stock
50 mg$356In StockIn Stock
100 mg$535In StockIn Stock
200 mg$735-In Stock
1 mL x 10 mM (in DMSO)$89In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:97.81%
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Product Introduction

Bioactivity
Description
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging.
Targets&IC50
HBV:0.13 μM
SynonymsAT 130
Chemical Properties
Molecular Weight488.33
FormulaC22H22BrN3O5
Cas No.211364-06-6
SmilesCOc1ccccc1\C(Br)=C(/NC(=O)c1ccc(cc1)[N+]([O-])=O)C(=O)N1CCCCC1
Relative Density.1.459 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 23 mg/mL (47.1 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0478 mL10.2390 mL20.4780 mL102.3898 mL
5 mM0.4096 mL2.0478 mL4.0956 mL20.4780 mL
10 mM0.2048 mL1.0239 mL2.0478 mL10.2390 mL
20 mM0.1024 mL0.5119 mL1.0239 mL5.1195 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

rtM204IrtL180MRNASynthesisRNA SynthesisRNAInhibitorinhibitHuh-7HepG2Hepatitis B virusHBVDNASynthesisDNA/RNA SynthesisDNA SynthesiscoreAT-130AT130
Related Tags: buy AT-130 | purchase AT-130 | AT-130 cost | order AT-130 | AT-130 chemical structure | AT-130 formula | AT-130 molecular weight
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