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Silychristin

Name: Silychristin
Brand: TargetMol
SKU: T3879
Price: 43 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3879Cas No. 33889-69-9

Alias Silychristin A, Silicristin

Silychristin (Silicristin) is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and lipoxygenase.

Silychristin

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Purity: 99.74%

Catalog No. T3879Alias Silychristin A, SilicristinCas No. 33889-69-9

Silychristin (Silicristin) is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and lipoxygenase.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$43	In Stock	In Stock
5 mg	$70	In Stock	In Stock
10 mg	$98	In Stock	In Stock
25 mg	$172	In Stock	In Stock
50 mg	$255	In Stock	In Stock
100 mg	$378	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$75	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.74%

Color:White

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COA

Product Introduction

Silychristin AI Summary

Silychristin inhibits theophylline-stimulated melanogenesis in mouse B16-4A5 cells at varying concentrations (1 uM, 3 uM, 10 uM, and 30 uM) after 72 hours, with inhibition percentages ranging from 1.3% to 17.4%, and shows low toxicity at 30 uM in the presence of 1 mM theophylline (inhibition < 8.8%). This compound also exhibits bioactivities related to tyrosinase inhibition, demonstrating binding affinity to mushroom tyrosinase and inhibiting both diphenolase and monophenolase activities with mixed type inhibition. It is characterized by specific binding constants, inhibition constants, and IC50 values for reducing dopachrome formation, indicating potential as a tyrosinase inhibitor. Additionally, Silychristin shows inhibition of binding to the Influenza A virus N-terminal GST-tagged polymerase acidic subunit with an IC50 value greater than 50000.0 nM and inhibits the His tagged SARS-CoV-2 PLpro enzyme with 19.8% inhibition at 100 uM and 3.4% inhibition at 20 uM, suggesting potential anti-SARS-CoV-2 PLpro activity..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Silychristin (Silicristin) is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and lipoxygenase.
Synonyms	Silychristin A, Silicristin

Chemical Properties

Molecular Weight	482.44
Formula	C₂₅H₂₂O₁₀
Cas No.	33889-69-9
Smiles	COc1cc(ccc1O)[C@@H]1Oc2c(cc(cc2O)[C@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2O)[C@H]1CO
Relative Density.	1.578g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (518.2 mM), Sonication is recommended.

Chloroform: Soluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0728 mL	10.3640 mL	20.7280 mL	103.6398 mL
5 mM	0.4146 mL	2.0728 mL	4.1456 mL	20.7280 mL
10 mM	0.2073 mL	1.0364 mL	2.0728 mL	10.3640 mL
20 mM	0.1036 mL	0.5182 mL	1.0364 mL	5.1820 mL
50 mM	0.0415 mL	0.2073 mL	0.4146 mL	2.0728 mL
100 mM	0.0207 mL	0.1036 mL	0.2073 mL	1.0364 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc