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KBU2046

🥰Excellent
Catalog No. T15646Cas No. 1143863-69-7

KBU2046 is an orally administered compound that inhibits cell motility and invasion, effectively suppressing cancer metastasis and extending lifespan. This compound uniquely targets and binds to chaperone heterocomplexes, selectively modifying the interaction of client proteins involved in motility regulation, while avoiding the characteristics typical of classical HSP90 inhibitors.

KBU2046

KBU2046

🥰Excellent
Purity: 99.89%
Catalog No. T15646Cas No. 1143863-69-7
KBU2046 is an orally administered compound that inhibits cell motility and invasion, effectively suppressing cancer metastasis and extending lifespan. This compound uniquely targets and binds to chaperone heterocomplexes, selectively modifying the interaction of client proteins involved in motility regulation, while avoiding the characteristics typical of classical HSP90 inhibitors.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$29In StockIn Stock
5 mg$48In StockIn Stock
10 mg$68In StockIn Stock
25 mg$143In StockIn Stock
50 mg$223In StockIn Stock
100 mg$338In StockIn Stock
200 mg$473In StockIn Stock
1 mL x 10 mM (in DMSO)$53In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.89%
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Product Introduction

Bioactivity
Description
KBU2046 is an orally administered compound that inhibits cell motility and invasion, effectively suppressing cancer metastasis and extending lifespan. This compound uniquely targets and binds to chaperone heterocomplexes, selectively modifying the interaction of client proteins involved in motility regulation, while avoiding the characteristics typical of classical HSP90 inhibitors.
Chemical Properties
Molecular Weight242.24
FormulaC15H11FO2
Cas No.1143863-69-7
SmilesFc1ccc(cc1)C1COc2ccccc2C1=O
Relative Density.1.31g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (185.77 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1281 mL20.6407 mL41.2814 mL206.4069 mL
5 mM0.8256 mL4.1281 mL8.2563 mL41.2814 mL
10 mM0.4128 mL2.0641 mL4.1281 mL20.6407 mL
20 mM0.2064 mL1.0320 mL2.0641 mL10.3203 mL
50 mM0.0826 mL0.4128 mL0.8256 mL4.1281 mL
100 mM0.0413 mL0.2064 mL0.4128 mL2.0641 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

KBU-2046KBU2046KBU 2046Inhibitorinhibit
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