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(E)-Akt inhibitor-IV

Name: (E)-Akt inhibitor-IV
Brand: TargetMol
SKU: T9393
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9393Cas No. 959841-49-7

Alias CS-1992, (E)-AKTIV

(E)-Akt inhibitor-IV ((E)-AKTIV) is an inhibitor of PI3K-Akt.

(E)-Akt inhibitor-IV

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Purity: 99.9%

Catalog No. T9393Alias CS-1992, (E)-AKTIVCas No. 959841-49-7

(E)-Akt inhibitor-IV ((E)-AKTIV) is an inhibitor of PI3K-Akt.

Pack Size	Price	Availability
1 mg	$50	In Stock
5 mg	$118	In Stock
10 mg	$189	In Stock
25 mg	$355	In Stock
50 mg	$493	In Stock
100 mg	$689	In Stock
200 mg	$973	In Stock
1 mL x 10 mM (in DMSO)	$159	In Stock

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Batch Information

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Purity:99.9%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	(E)-Akt inhibitor-IV ((E)-AKTIV) is an inhibitor of PI3K-Akt.
In vitro	(E)-Akt inhibitor-IV shows little effects on the growth of 184B5 non-cancer cells at the average GI20?doses
Synonyms	CS-1992, (E)-AKTIV

Chemical Properties

Molecular Weight	616.56
Formula	C₃₁H₂₉IN₄S
Cas No.	959841-49-7
Smiles	CCN(C1/C=C/N(C)c2ccccc2)c(cc(cc2)-c3nc(cccc4)c4s3)c2N1c1ccccc1.I
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (81.1 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6219 mL	8.1095 mL	16.2190 mL	81.0951 mL
5 mM	0.3244 mL	1.6219 mL	3.2438 mL	16.2190 mL
10 mM	0.1622 mL	0.8110 mL	1.6219 mL	8.1095 mL
20 mM	0.0811 mL	0.4055 mL	0.8110 mL	4.0548 mL
50 mM	0.0324 mL	0.1622 mL	0.3244 mL	1.6219 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc