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Anhydrosimvastatin

Name: Anhydrosimvastatin
Brand: TargetMol
SKU: T10324
Price: 139 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10324Cas No. 210980-68-0

Alias Dehydro simvastatin

Anhydrosimvastatin (Dehydro simvastatin) is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.

Anhydrosimvastatin

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Purity: 99.63%

Catalog No. T10324Alias Dehydro simvastatinCas No. 210980-68-0

Anhydrosimvastatin (Dehydro simvastatin) is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.

Pack Size	Price	Availability
1 mg	$139	In Stock
5 mg	$313	In Stock
10 mg	$453	In Stock
25 mg	$687	In Stock
50 mg	$948	In Stock
100 mg	$1,270	In Stock
1 mL x 10 mM (in DMSO)	$345	In Stock

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Batch Information

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Purity:99.63%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Anhydrosimvastatin (Dehydro simvastatin) is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.
Synonyms	Dehydro simvastatin

Chemical Properties

Molecular Weight	400.55
Formula	C₂₅H₃₆O₄
Cas No.	210980-68-0
Smiles	O(C(C(CC)(C)C)=O)[C@@H]1[C@]2(C(C=C[C@H](C)[C@@H]2CC[C@H]3OC(=O)C=CC3)=C[C@H](C)C1)[H]
Relative Density.	1.07 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (124.83 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4966 mL	12.4828 mL	24.9657 mL	124.8284 mL
5 mM	0.4993 mL	2.4966 mL	4.9931 mL	24.9657 mL
10 mM	0.2497 mL	1.2483 mL	2.4966 mL	12.4828 mL
20 mM	0.1248 mL	0.6241 mL	1.2483 mL	6.2414 mL
50 mM	0.0499 mL	0.2497 mL	0.4993 mL	2.4966 mL
100 mM	0.0250 mL	0.1248 mL	0.2497 mL	1.2483 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc