Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

HDAC3-IN-T247

🥰Excellent
Catalog No. T24131Cas No. 1451042-18-4
Alias T247, HDAC3 inhibitor-T247, HDAC3 inhibitor T247, HDAC3 IN T247

HDAC3-IN-T247 (HDAC3 inhibitor T247) is a selective and potent histone deacetylase 3 (HDAC3) inhibitor with anticancer and antiviral activities.HDAC3-IN-T247 induces NF-κB acetylation in human colon cancer HCT116 cells in a dose-dependent manner.HDAC3-IN-T247 inhibits cancer cell proliferation. HDAC3-IN-T247 inhibits cancer cell proliferation.

HDAC3-IN-T247

HDAC3-IN-T247

🥰Excellent
Purity: 98.94%
Catalog No. T24131Alias T247, HDAC3 inhibitor-T247, HDAC3 inhibitor T247, HDAC3 IN T247Cas No. 1451042-18-4
HDAC3-IN-T247 (HDAC3 inhibitor T247) is a selective and potent histone deacetylase 3 (HDAC3) inhibitor with anticancer and antiviral activities.HDAC3-IN-T247 induces NF-κB acetylation in human colon cancer HCT116 cells in a dose-dependent manner.HDAC3-IN-T247 inhibits cancer cell proliferation. HDAC3-IN-T247 inhibits cancer cell proliferation.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$84-In Stock
5 mg$198-In Stock
10 mg$328-In Stock
25 mg$677-In Stock
50 mg$963-In Stock
100 mg$1,280-In Stock
1 mL x 10 mM (in DMSO)$226-In Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:98.94%
Contact us for more batch information

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity
Description
HDAC3-IN-T247 (HDAC3 inhibitor T247) is a selective and potent histone deacetylase 3 (HDAC3) inhibitor with anticancer and antiviral activities.HDAC3-IN-T247 induces NF-κB acetylation in human colon cancer HCT116 cells in a dose-dependent manner.HDAC3-IN-T247 inhibits cancer cell proliferation. HDAC3-IN-T247 inhibits cancer cell proliferation.
Targets&IC50
HDAC4:>100 μM, HDAC1:19 μM, HDAC6:>100 μM, HDAC8:>100 μM, HDAC3:0.24 μM
SynonymsT247, HDAC3 inhibitor-T247, HDAC3 inhibitor T247, HDAC3 IN T247
Chemical Properties
Molecular Weight389.47
FormulaC21H19N5OS
Cas No.1451042-18-4
SmilesNc1ccccc1NC(=O)c1ccc(cc1)-c1cn(CCc2ccsc2)nn1
Relative Density.1.34 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 20 mg/mL (51.35 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5676 mL12.8380 mL25.6759 mL128.3796 mL
5 mM0.5135 mL2.5676 mL5.1352 mL25.6759 mL
10 mM0.2568 mL1.2838 mL2.5676 mL12.8380 mL
20 mM0.1284 mL0.6419 mL1.2838 mL6.4190 mL
50 mM0.0514 mL0.2568 mL0.5135 mL2.5676 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

T-247T 247HistoneDemethylaseHistone DemethylaseHDAC3INT-247HDAC3-IN-T-247HDAC3-IN-T247HDAC-3-IN-T247HDAC3INT247HDAC3-IN-T 247HDAC3INT 247HDAC3 inhibitor-T-247HDAC3 inhibitor-T 247HDAC3 inhibitor T-247HDAC3 inhibitor T 247HDAC3 IN T-247HDAC3 IN T 247Antiviral
Related Tags: buy HDAC3-IN-T247 | purchase HDAC3-IN-T247 | HDAC3-IN-T247 cost | order HDAC3-IN-T247 | HDAC3-IN-T247 chemical structure | HDAC3-IN-T247 formula | HDAC3-IN-T247 molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.