Shopping Cart

Your shopping cart is currently empty

WAY-169916

Name: WAY-169916
Brand: TargetMol
SKU: T8981
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

🥰Excellent

Catalog No. T8981Cas No. 669764-18-5

Alias WAY169916, WAY 169916

WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER), inhibiting NF-kB transcriptional activity while being devoid of conventional estrogenic activity.

WAY-169916

Copy Product Info

🥰Excellent

Purity: 98.64%

Catalog No. T8981Alias WAY169916, WAY 169916Cas No. 669764-18-5

WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER), inhibiting NF-kB transcriptional activity while being devoid of conventional estrogenic activity.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$35	In Stock	In Stock
5 mg	$58	In Stock	In Stock
10 mg	$98	In Stock	In Stock
25 mg	$208	In Stock	In Stock
50 mg	$347	In Stock	In Stock
100 mg	$500	In Stock	In Stock
200 mg	$689	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$86	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98.64%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

WAY-169916 AI Summary

WAY-169916 exhibits bioactivities related to the inhibition and modulation of gene expression in liver cells and estrogen receptor pathways. It shows significant inhibitory effects on NF-kappaB transcription, as well as on MHC, VCAM1, and TNFalpha mRNA levels in a high fat diet-fed mouse liver model. Additionally, it demonstrates moderate displacement of [3H]E2 from ERalpha and ERbeta ligand binding domains, indicating potential interactions with estrogen receptors..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER), inhibiting NF-kB transcriptional activity while being devoid of conventional estrogenic activity.
Synonyms	WAY169916, WAY 169916

Chemical Properties

Molecular Weight	334.29
Formula	C₁₇H₁₃F₃N₂O₂
Cas No.	669764-18-5
Smiles	C(F)(F)(F)C1=C2C(C(=NN2CC=C)C3=C(O)C=C(O)C=C3)=CC=C1
Relative Density.	1.37 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (164.53 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9914 mL	14.9571 mL	29.9141 mL	149.5707 mL
5 mM	0.5983 mL	2.9914 mL	5.9828 mL	29.9141 mL
10 mM	0.2991 mL	1.4957 mL	2.9914 mL	14.9571 mL
20 mM	0.1496 mL	0.7479 mL	1.4957 mL	7.4785 mL
50 mM	0.0598 mL	0.2991 mL	0.5983 mL	2.9914 mL
100 mM	0.0299 mL	0.1496 mL	0.2991 mL	1.4957 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc