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Remodelin hydrobromide

Name: Remodelin hydrobromide
Brand: TargetMol
SKU: T6133
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6133Cas No. 1622921-15-6

Alias Remodelin HBR, Remodelin

Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.

Remodelin hydrobromide

🥰Excellent

Purity: 99.84%

Catalog No. T6133Alias Remodelin HBR, RemodelinCas No. 1622921-15-6

Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$34	In Stock	In Stock
5 mg	$52	In Stock	In Stock
10 mg	$79	In Stock	In Stock
25 mg	$148	In Stock	In Stock
50 mg	$262	In Stock	In Stock
100 mg	$372	In Stock	In Stock
200 mg	$556	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$58	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.84%

Color:Yellow

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COA

Product Introduction

Bioactivity

Description	Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
In vivo	Remodelin restores nuclear morphology and enhances the resilience of the nucleus in HGPS cells by depleting LMNA through microtubule reorganization, mediated by its inhibition of NAT10.
Synonyms	Remodelin HBR, Remodelin

Chemical Properties

Molecular Weight	363.275
Formula	C₁₅H₁₅BrN₄S
Cas No.	1622921-15-6
Smiles	Br.N#CC=1C=CC(=CC1)C=2N=C(SC2)NN=C3CCCC3
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (412.91 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (11.01 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7527 mL	13.7637 mL	27.5274 mL	137.6368 mL
5 mM	0.5505 mL	2.7527 mL	5.5055 mL	27.5274 mL
10 mM	0.2753 mL	1.3764 mL	2.7527 mL	13.7637 mL
20 mM	0.1376 mL	0.6882 mL	1.3764 mL	6.8818 mL
50 mM	0.0551 mL	0.2753 mL	0.5505 mL	2.7527 mL
100 mM	0.0275 mL	0.1376 mL	0.2753 mL	1.3764 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc