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BAY 59-9435

Name: BAY 59-9435
Brand: TargetMol
SKU: T11577
Rating: 4.5 (1 reviews)

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Catalog No. T11577Cas No. 654059-21-9

Alias HSL-IN-2

HSL-IN-2 is a selective inhibitor of Hormone Sensitive Lipase (HSL; IC50: 0.023 μM).

BAY 59-9435

😃Good

Catalog No. T11577Alias HSL-IN-2Cas No. 654059-21-9

HSL-IN-2 is a selective inhibitor of Hormone Sensitive Lipase (HSL; IC50: 0.023 μM).

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,520	6-8 weeks	6-8 weeks
50 mg	$1,980	6-8 weeks	6-8 weeks
100 mg	$2,500	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	HSL-IN-2 is a selective inhibitor of Hormone Sensitive Lipase (HSL; IC50: 0.023 μM).
Targets&IC50	HSL:0.023 μM
Synonyms	HSL-IN-2

Chemical Properties

Molecular Weight	266.34
Formula	C₁₄H₂₂N₂O₃
Cas No.	654059-21-9
Smiles	CC(C)c1c(C)n(oc1=O)C(=O)N1CCC[C@H](C)C1
Relative Density.	1.140 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (938.65 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 5 mg/mL (18.77 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7546 mL	18.7730 mL	37.5460 mL	187.7300 mL
5 mM	0.7509 mL	3.7546 mL	7.5092 mL	37.5460 mL
10 mM	0.3755 mL	1.8773 mL	3.7546 mL	18.7730 mL
20 mM	0.1877 mL	0.9386 mL	1.8773 mL	9.3865 mL
50 mM	0.0751 mL	0.3755 mL	0.7509 mL	3.7546 mL
100 mM	0.0375 mL	0.1877 mL	0.3755 mL	1.8773 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc