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AZD3264

Name: AZD3264
Brand: TargetMol
SKU: T6771
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6771Cas No. 1609281-86-8

AZD3264 is a new type IKK2 inhibitor.

AZD3264

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Purity: 99.17%

Catalog No. T6771Cas No. 1609281-86-8

AZD3264 is a new type IKK2 inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$44	In Stock	In Stock
2 mg	$64	In Stock	In Stock
5 mg	$105	In Stock	In Stock
10 mg	$163	In Stock	In Stock
25 mg	$328	In Stock	In Stock
50 mg	$528	In Stock	In Stock
100 mg	$847	In Stock	In Stock
500 mg	$1,690	-	In Stock
1 mL x 10 mM (in DMSO)	$116	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.17%

Appearance:Solid

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	AZD3264 is a new type IKK2 inhibitor.
In vitro	AZD3264, by inhibiting IKK2, prevents in?ammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis. [1]

Chemical Properties

Molecular Weight	441.5
Formula	C₂₁H₂₃N₅O₄S
Cas No.	1609281-86-8
Smiles	Cc1noc(C)c1-c1ccc(-c2cc(C(N)=O)c(NC(N)=O)s2)c(O[C@H]2CCNC2)c1
Relative Density.	1.371 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 2 mg/mL (4.53 mM), Heating is recommended.

DMSO: 82 mg/mL (185.73 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (7.47 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2650 mL	11.3250 mL	22.6501 mL	113.2503 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	0.4530 mL	2.2650 mL	4.5300 mL	22.6501 mL
10 mM	0.2265 mL	1.1325 mL	2.2650 mL	11.3250 mL
20 mM	0.1133 mL	0.5663 mL	1.1325 mL	5.6625 mL
50 mM	0.0453 mL	0.2265 mL	0.4530 mL	2.2650 mL
100 mM	0.0227 mL	0.1133 mL	0.2265 mL	1.1325 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc