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Sacubitril Enantiomer

Name: Sacubitril Enantiomer
Brand: TargetMol
SKU: T19112L
Price: 97 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19112L

Alias ahu377 isomer 2, 2R,4S-Sacubitril

Sacubitril Enantiomer (ahu377 isomer 2) is the enantiomer of Sacubitril which is a neprilysin inhibitor.

Sacubitril Enantiomer

🥰Excellent

Purity: 99.89%

Catalog No. T19112LAlias ahu377 isomer 2, 2R,4S-Sacubitril

Sacubitril Enantiomer (ahu377 isomer 2) is the enantiomer of Sacubitril which is a neprilysin inhibitor.

Pack Size	Price	Availability
1 mg	$97	In Stock
5 mg	$297	In Stock
10 mg	$445	In Stock
25 mg	$735	In Stock
50 mg	$987	In Stock
1 mL x 10 mM (in DMSO)	$328	In Stock

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Batch Information

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Purity:99.89%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Sacubitril Enantiomer (ahu377 isomer 2) is the enantiomer of Sacubitril which is a neprilysin inhibitor.
Synonyms	ahu377 isomer 2, 2R,4S-Sacubitril

Chemical Properties

Molecular Weight	430.53
Formula	C₂₄H₂₈NO₅ 1/2Ca
Smiles	O=C([O-])CCC(N[C@H](C[C@H](C)C(OCC)=O)CC1=CC=C(C2=CC=CC=C2)C=C1)=O.O=C([O-])CCC(N[C@H](C[C@H](C)C(OCC)=O)CC3=CC=C(C4=CC=CC=C4)C=C3)=O.[Ca+2]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (127.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3227 mL	11.6136 mL	23.2272 mL	116.1359 mL
5 mM	0.4645 mL	2.3227 mL	4.6454 mL	23.2272 mL
10 mM	0.2323 mL	1.1614 mL	2.3227 mL	11.6136 mL
20 mM	0.1161 mL	0.5807 mL	1.1614 mL	5.8068 mL
50 mM	0.0465 mL	0.2323 mL	0.4645 mL	2.3227 mL
100 mM	0.0232 mL	0.1161 mL	0.2323 mL	1.1614 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc