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Gymnoside III

Name: Gymnoside III
Brand: TargetMol
SKU: TN1720
Price: 91 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1720Cas No. 899430-03-6

Gymnoside III is a natural product from Gymnadenia conopsea.

Gymnoside III

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Purity: 99.79%

Catalog No. TN1720Cas No. 899430-03-6

Gymnoside III is a natural product from Gymnadenia conopsea.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$91	In Stock	In Stock
5 mg	$217	In Stock	In Stock
10 mg	$320	In Stock	In Stock
25 mg	$538	In Stock	In Stock
50 mg	$779	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$330	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.79%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Gymnoside III AI Summary

Gymnoside III exhibits hepatoprotective activity against D-GalN-induced toxicity in human HL-7702 cells and APAP-induced toxicity in human HepG2 cells. In the D-GalN-induced toxicity assay, the compound showed a cell survival rate of 39.0% at a 10 μM concentration after preincubation for 48 hours followed by D-GalN stimulation for 8 hours. Additionally, in the APAP-induced toxicity assay, the compound demonstrated a cell survival rate of 14.0% at a 10 μM concentration after 48 hours. These results suggest that Gymnoside III possesses significant hepatoprotective properties in these cellular models..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Gymnoside III is a natural product from Gymnadenia conopsea.

Chemical Properties

Molecular Weight	930.9
Formula	C₄₂H₅₈O₂₃
Cas No.	899430-03-6
Smiles	[C@@](O[C@@H]1O[C@H](COC(C)=O)[C@@H](O)[C@H](O)[C@H]1O)(C(OCC2=CC=C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C=C2)=O)(CC(OCC4=CC=C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C=C4)=O)CC(C)C
Relative Density.	1.55 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (59.08 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0742 mL	5.3711 mL	10.7423 mL	53.7115 mL
5 mM	0.2148 mL	1.0742 mL	2.1485 mL	10.7423 mL
10 mM	0.1074 mL	0.5371 mL	1.0742 mL	5.3711 mL
20 mM	0.0537 mL	0.2686 mL	0.5371 mL	2.6856 mL
50 mM	0.0215 mL	0.1074 mL	0.2148 mL	1.0742 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc