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NH2-UAMC1110 TFA

Name: NH2-UAMC1110 TFA
Brand: TargetMol
SKU: T78179
Price: 56 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T78179Cas No. 2990021-73-1

NH2-UAMC1110 TFA is a derivative of UAMC1110 bearing an aminobutoxy group for the synthesis of FAPI-QS. UAMC1110 is a novel selective fibroblast-activated protein (fap) inhibitor exhibiting low nanomolar inhibition of the related dipeptidyl peptidases (dpps), dppiv, dpp9, dppii, and (prep). dppiv, dpp9, dppii, and (prep).

NH2-UAMC1110 TFA

🥰Excellent

Purity: 99.02%

Catalog No. T78179Cas No. 2990021-73-1

Pack Size	Price	Availability
1 mg	$56	In Stock
5 mg	$172	In Stock
10 mg	$278	In Stock

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Batch Information

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Purity:99.02%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	545.46
Formula	C₂₃H₂₄F₅N₅O₅
Cas No.	2990021-73-1
Smiles	C(C(O)=O)(F)(F)F.C(NCC(=O)N1[C@H](C#N)CC(F)(F)C1)(=O)C=2C3=C(C=CC(OCCCCN)=C3)N=CC2

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 200 mg/mL (366.66 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.8333 mL	9.1666 mL	18.3332 mL	91.6658 mL
5 mM	0.3667 mL	1.8333 mL	3.6666 mL	18.3332 mL
10 mM	0.1833 mL	0.9167 mL	1.8333 mL	9.1666 mL
20 mM	0.0917 mL	0.4583 mL	0.9167 mL	4.5833 mL
50 mM	0.0367 mL	0.1833 mL	0.3667 mL	1.8333 mL
100 mM	0.0183 mL	0.0917 mL	0.1833 mL	0.9167 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc