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CNDAC hydrochloride

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Catalog No. T13621Cas No. 134665-72-8

CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.

CNDAC hydrochloride

CNDAC hydrochloride

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Purity: 99.45%
Catalog No. T13621Cas No. 134665-72-8
CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$116-In Stock
5 mg$288-In Stock
10 mg$448-In Stock
25 mg$643-In Stock
50 mg$828-In Stock
100 mg$1,320-In Stock
200 mg$1,780-In Stock
1 mL x 10 mM (in DMSO)$263-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.45%
Color:White
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Product Introduction

CNDAC hydrochloride AI Summary
CNDAC hydrochloride exhibits inhibitory activity against various cancer cell lines in vitro, with IC50 values ranging from 530.0 nM to over 350000.0 nM. Additionally, it demonstrates significant weight change effects and high percent inhibition in a mouse sarcoma model after oral administration at various doses, resulting in a high percentage of survivors. These findings suggest that CNDAC hydrochloride possesses promising anti-cancer properties..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.
Chemical Properties
Molecular Weight288.69
FormulaC10H13ClN4O4
Cas No.134665-72-8
SmilesCl.Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2C#N)c(=O)n1
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 123 mg/mL (426.06 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4639 mL17.3196 mL34.6392 mL173.1962 mL
5 mM0.6928 mL3.4639 mL6.9278 mL34.6392 mL
10 mM0.3464 mL1.7320 mL3.4639 mL17.3196 mL
20 mM0.1732 mL0.8660 mL1.7320 mL8.6598 mL
50 mM0.0693 mL0.3464 mL0.6928 mL3.4639 mL
100 mM0.0346 mL0.1732 mL0.3464 mL1.7320 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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