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Vesamicol hydrochloride

Name: Vesamicol hydrochloride
Brand: TargetMol
SKU: T22486
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22486Cas No. 120447-62-3

Alias (±)-AH5183 hydrochloride

Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.

Vesamicol hydrochloride

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Purity: 99.88%

Catalog No. T22486Alias (±)-AH5183 hydrochlorideCas No. 120447-62-3

Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.

Pack Size	Price	Availability
2 mg	$33	In Stock
5 mg	$52	In Stock
10 mg	$79	In Stock
25 mg	$158	In Stock
50 mg	$235	In Stock
100 mg	$347	In Stock

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Batch Information

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Purity:99.88%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.
Targets&IC50	σ1 receptor:26 nM (Ki), Acetylcholine transport (vesicular):2 nM (Ki), σ2 receptor:34 nM (Ki)
Synonyms	(±)-AH5183 hydrochloride

Chemical Properties

Molecular Weight	295.85
Formula	C₁₇H₂₆ClNO
Cas No.	120447-62-3
Smiles	Cl.OC1CCCCC1N1CCC(CC1)C1=CC=CC=C1
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: < 5.92 mg/mL, Sonication is recommended.

DMSO: 18.7 mg/mL (63.4 mM), Sonication and heating to 60℃ are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3801 mL	16.9005 mL	33.8009 mL	169.0046 mL
5 mM	0.6760 mL	3.3801 mL	6.7602 mL	33.8009 mL
10 mM	0.3380 mL	1.6900 mL	3.3801 mL	16.9005 mL
20 mM	0.1690 mL	0.8450 mL	1.6900 mL	8.4502 mL
50 mM	0.0676 mL	0.3380 mL	0.6760 mL	3.3801 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc