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rel-(1R,2R)-Vesamicol Hydrochloride

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Catalog No. T22486Cas No. 120447-62-3
Alias (±)-AH5183 hydrochloride

rel-(1R,2R)-Vesamicol Hydrochloride is an isomer of Vesamicol Hydrochloride and can be employed in biochemical experiments.

rel-(1R,2R)-Vesamicol Hydrochloride
Other Forms of rel-(1R,2R)-Vesamicol Hydrochloride:

rel-(1R,2R)-Vesamicol Hydrochloride

🥰Excellent
Purity: 99.88%
Catalog No. T22486Alias (±)-AH5183 hydrochlorideCas No. 120447-62-3
rel-(1R,2R)-Vesamicol Hydrochloride is an isomer of Vesamicol Hydrochloride and can be employed in biochemical experiments.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$33In StockIn Stock
5 mg$52In StockIn Stock
10 mg$79In StockIn Stock
25 mg$158In StockIn Stock
50 mg$235In StockIn Stock
100 mg$347-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.88%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
rel-(1R,2R)-Vesamicol Hydrochloride is an isomer of Vesamicol Hydrochloride and can be employed in biochemical experiments.
Targets&IC50
Acetylcholine transport (vesicular):2 nM (Ki), σ2 receptor:34 nM (Ki), σ1 receptor:26 nM (Ki)
Synonyms(±)-AH5183 hydrochloride
Chemical Properties
Molecular Weight295.85
FormulaC17H26ClNO
Cas No.120447-62-3
SmilesCl.OC1CCCCC1N1CCC(CC1)C1=CC=CC=C1
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: < 5.92 mg/mL, Sonication is recommended.
DMSO: 18.7 mg/mL (63.4 mM), Sonication and heating to 60℃ are recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.76 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3801 mL16.9005 mL33.8009 mL169.0046 mL
5 mM0.6760 mL3.3801 mL6.7602 mL33.8009 mL
10 mM0.3380 mL1.6900 mL3.3801 mL16.9005 mL
20 mM0.1690 mL0.8450 mL1.6900 mL8.4502 mL
50 mM0.0676 mL0.3380 mL0.6760 mL3.3801 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Vesamicol HydrochlorideAH-5183 HydrochlorideAH5183 HydrochlorideAH 5183 HydrochlorideAChR
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