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NK01-63

Name: NK01-63
Brand: TargetMol
SKU: T60045
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T60045Cas No. 2922281-15-8

Alias NK01 63

NK01-63 (Coronastat) is a potent inhibitor of the SARS-CoV-2 3CL protease.

NK01-63

😃Good

Catalog No. T60045Alias NK01 63Cas No. 2922281-15-8

NK01-63 (Coronastat) is a potent inhibitor of the SARS-CoV-2 3CL protease.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$63	Backorder	Backorder
2 mg	$93	Backorder	Backorder
5 mg	$157	Backorder	Backorder
10 mg	$233	Backorder	Backorder
25 mg	$382	Backorder	Backorder
50 mg	$529	Backorder	Backorder
100 mg	$714	Backorder	Backorder

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	NK01-63 (Coronastat) is a potent inhibitor of the SARS-CoV-2 3CL protease.
Synonyms	NK01 63

Chemical Properties

Molecular Weight	575.53
Formula	C₂₂H₂₉F₃N₃NaO₈S
Cas No.	2922281-15-8
Smiles	CC(C)C[C@@H](C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S(=O)(=O)[O-])NC(=O)OCC2=CC(=CC=C2)C(F)(F)F.[Na+]
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (156.38 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7375 mL	8.6876 mL	17.3753 mL	86.8764 mL
5 mM	0.3475 mL	1.7375 mL	3.4751 mL	17.3753 mL
10 mM	0.1738 mL	0.8688 mL	1.7375 mL	8.6876 mL
20 mM	0.0869 mL	0.4344 mL	0.8688 mL	4.3438 mL
50 mM	0.0348 mL	0.1738 mL	0.3475 mL	1.7375 mL
100 mM	0.0174 mL	0.0869 mL	0.1738 mL	0.8688 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc