Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BSJ-04-122 is a covalent MKK4/7 dual inhibitor that inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively.BSJ-04-122 can be used for cancer research.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 35.00 | |
5 mg | In stock | $ 75.00 | |
10 mg | In stock | $ 120.00 | |
25 mg | In stock | $ 241.00 | |
50 mg | In stock | $ 390.00 | |
100 mg | In stock | $ 623.00 |
Description | BSJ-04-122 is a covalent MKK4/7 dual inhibitor that inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively.BSJ-04-122 can be used for cancer research. |
Targets&IC50 | MKK4:4 nM, MKK7:181 nM |
In vitro |
BSJ-04-122 has inhibitory activity against MKK4 and MKK7 with IC50 values of 4 nM and 181 nM respectively.[1] BSJ-04-122 (1, 5, 10 μM; 6 h) induces a strong reduction in JNK phosphorylation.[1] BSJ-04-122 (0, 1.25, 2.5, 5, 10, 20 μM; 72 h) showed enhanced antiproliferative effects when combined with JNK-IN-8.[1] |
Molecular Weight | 313.74 |
Formula | C15H12ClN5O |
CAS No. | 2513289-74-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (159.37 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BSJ-04-122 2513289-74-0 MAPK JNK inhibitor inhibit