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Hexyl gallate

Name: Hexyl gallate
Brand: TargetMol
SKU: T11558
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T11558Cas No. 1087-26-9

Alias Hexyl 3,4,5-trihydroxybenzoate, Gallic acid hexyl ester

Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).

Hexyl gallate

🥰Excellent

Purity: 99.78%

Catalog No. T11558Alias Hexyl 3,4,5-trihydroxybenzoate, Gallic acid hexyl esterCas No. 1087-26-9

Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$31	In Stock	In Stock
50 mg	$44	In Stock	In Stock
100 mg	$64	In Stock	In Stock
200 mg	$109	In Stock	In Stock
500 mg	$183	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.78%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).
Targets&IC50	Antimalarial:0.11 mM
In vitro	Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) selectively inhibit RhlR-dependent production of rhamnolipid and pyocyanin, impacting only Rhl-regulated pathways while preserving elastase production and biofilm formation controlled by the Las system. These compounds show pigment inhibition at concentrations of 10-30 μM and exhibit notable antibacterial properties. Hexyl gallates also suppress N-butanoyl homoserine lactone (BHL) production at 100 and 300 μM, without affecting N-(3-oxododecanoyl)-l-homoserine lactone (OdDHL) and 2-heptyl-3-hydroxy-4(1H) quinolone (PQS) synthesis. As a promising antimicrobial alternative to copper compounds, Hexyl gallates effectively inhibit Xanthomonas citri growth at 30-50 μg/ml by targeting the bacterium's membrane, demonstrating a dose-responsive behavior.
Synonyms	Hexyl 3,4,5-trihydroxybenzoate, Gallic acid hexyl ester

Chemical Properties

Molecular Weight	254.28
Formula	C₁₃H₁₈O₅
Cas No.	1087-26-9
Smiles	CCCCCCOC(=O)c1cc(O)c(O)c(O)c1
Relative Density.	1.239 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (196.63 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.87 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9327 mL	19.6634 mL	39.3267 mL	196.6336 mL
5 mM	0.7865 mL	3.9327 mL	7.8653 mL	39.3267 mL
10 mM	0.3933 mL	1.9663 mL	3.9327 mL	19.6634 mL
20 mM	0.1966 mL	0.9832 mL	1.9663 mL	9.8317 mL
50 mM	0.0787 mL	0.3933 mL	0.7865 mL	3.9327 mL
100 mM	0.0393 mL	0.1966 mL	0.3933 mL	1.9663 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc