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Chlorquinaldol

Name: Chlorquinaldol
Brand: TargetMol
SKU: T0908
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0908Cas No. 72-80-0

Alias Chloquinan, 5,7-Dichloro-8-hydroxy-2-methylquinoline

Chlorquinaldol (5,7-Dichloro-8-hydroxy-2-methylquinoline) is a Standardized Chemical Allergen. The physiologic effect of chlorquinaldol is by means of Increased Histamine Release, and Cell-mediated Immunity.

Chlorquinaldol

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Purity: 99.77%

Catalog No. T0908Alias Chloquinan, 5,7-Dichloro-8-hydroxy-2-methylquinolineCas No. 72-80-0

Pack Size	Price	Availability	Quantity
1 g	$34	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Purity:99.77%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Chlorquinaldol (5,7-Dichloro-8-hydroxy-2-methylquinoline) is a Standardized Chemical Allergen. The physiologic effect of chlorquinaldol is by means of Increased Histamine Release, and Cell-mediated Immunity.
In vivo	Chlorquinaldol, a derivative of hydroxy-8-quinoline, exhibits enhanced bactericidal activity in duodenal-pancreatic secretions. At concentrations of 0.1-0.2% (w/v), Chlorquinaldol reduced Neisseria gonorrhoeae and Chlamydia trachomatis by approximately 10^4 within 60 minutes.
Synonyms	Chloquinan, 5,7-Dichloro-8-hydroxy-2-methylquinoline

Chemical Properties

Molecular Weight	228.07
Formula	C₁₀H₇Cl₂NO
Cas No.	72-80-0
Smiles	OC=1C2=C(C(Cl)=CC1Cl)C=CC(C)=N2
Relative Density.	1.467 g/cm3
Color	Brown
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 6 mg/mL (26.31 mM), Sonication is recommended.

DMSO: 50 mg/mL (219.23 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.77 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3846 mL	21.9231 mL	43.8462 mL	219.2309 mL
5 mM	0.8769 mL	4.3846 mL	8.7692 mL	43.8462 mL
10 mM	0.4385 mL	2.1923 mL	4.3846 mL	21.9231 mL
20 mM	0.2192 mL	1.0962 mL	2.1923 mL	10.9615 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0877 mL	0.4385 mL	0.8769 mL	4.3846 mL
100 mM	0.0438 mL	0.2192 mL	0.4385 mL	2.1923 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc