Shopping Cart

Your shopping cart is currently empty

Levofloxacin hydrochloride

Name: Levofloxacin hydrochloride
Brand: TargetMol
SKU: T8747
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

🥰Excellent

Catalog No. T8747Cas No. 177325-13-2

Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.

Levofloxacin hydrochloride

Copy Product Info

🥰Excellent

Purity: 99.98%

Catalog No. T8747Cas No. 177325-13-2

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$37	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.98%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Levofloxacin hydrochloride AI Summary

Levofloxacin hydrochloride exhibits notable antibacterial activity against Bacillus subtilis and Staphylococcus aureus, with inhibitory zone diameters decreasing in a dose-dependent manner. Pharmacokinetic and metabolic studies reveal varying drug levels in blood to plasma ratios across species, indicating differences in bioavailability. The compound demonstrates moderate to high plasma protein binding and undergoes extensive metabolism, particularly glucuronidation, with significant excretion through bile and urine. Its relatively short half-life in humans points to a rapid clearance from the body..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Chemical Properties

Molecular Weight	397.8
Formula	C₁₈H₂₁ClFN₃O₄
Cas No.	177325-13-2
Smiles	Cl.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O
Relative Density.	no data available

Storage & Solubility Information

Storage

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 7.14 mg/mL (17.95 mM), Sonication is recommended.

H2O: 100 mg/mL (251.38 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.5138 mL	12.5691 mL	25.1383 mL	125.6913 mL
5 mM	0.5028 mL	2.5138 mL	5.0277 mL	25.1383 mL
10 mM	0.2514 mL	1.2569 mL	2.5138 mL	12.5691 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.1257 mL	0.6285 mL	1.2569 mL	6.2846 mL
50 mM	0.0503 mL	0.2514 mL	0.5028 mL	2.5138 mL
100 mM	0.0251 mL	0.1257 mL	0.2514 mL	1.2569 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc