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TH-Z145

Name: TH-Z145
Brand: TargetMol
SKU: T73450
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T73450Cas No. 2260887-57-6

TH-Z145 is a potent FPPS inhibitor for the study of myeloma and lung cancer.

TH-Z145

🥰Excellent

Purity: 98.29%

Catalog No. T73450Cas No. 2260887-57-6

TH-Z145 is a potent FPPS inhibitor for the study of myeloma and lung cancer.

Pack Size	Price	Availability
1 mg	$44	In Stock
5 mg	$105	In Stock
10 mg	$172	In Stock
25 mg	$355	In Stock
50 mg	$572	In Stock
100 mg	$913	In Stock
1 mL x 10 mM (in DMSO)	$116	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.29%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	TH-Z145 is a potent FPPS inhibitor for the study of myeloma and lung cancer.
In vivo	In a pathogenic influenza model, TH-Z145 (20 μg, i.p.) demonstrates strong prophylactic effects[1].

Chemical Properties

Molecular Weight	394.34
Formula	C₁₆H₂₈O₇P₂
Cas No.	2260887-57-6
Smiles	C(C(P(=O)(O)O)P(=O)(O)O)C1=CC(OCCCCCCCC)=CC=C1

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (202.87 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5359 mL	12.6794 mL	25.3588 mL	126.7941 mL
5 mM	0.5072 mL	2.5359 mL	5.0718 mL	25.3588 mL
10 mM	0.2536 mL	1.2679 mL	2.5359 mL	12.6794 mL
20 mM	0.1268 mL	0.6340 mL	1.2679 mL	6.3397 mL
50 mM	0.0507 mL	0.2536 mL	0.5072 mL	2.5359 mL
100 mM	0.0254 mL	0.1268 mL	0.2536 mL	1.2679 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc