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Sebetralstat

Name: Sebetralstat
Brand: TargetMol
SKU: T39350
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T39350Cas No. 1933514-13-6

Alias KVD900

Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases.

Sebetralstat

🥰Excellent

Purity: 99.85%

Catalog No. T39350Alias KVD900Cas No. 1933514-13-6

Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases.

Pack Size	Price	Availability
1 mg	$30	In Stock
5 mg	$68	In Stock
10 mg	$107	In Stock
25 mg	$197	In Stock
50 mg	$293	In Stock
100 mg	$435	In Stock
1 mL x 10 mM (in DMSO)	$76	In Stock

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Batch Information

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Purity:99.85%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases.
Synonyms	KVD900

Chemical Properties

Molecular Weight	491.51
Formula	C₂₆H₂₆FN₅O₄
Cas No.	1933514-13-6
Smiles	COCc1nn(Cc2ccc(Cn3ccccc3=O)cc2)cc1C(=O)NCc1nccc(OC)c1F

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 112.5 mg/mL (228.89 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0345 mL	10.1727 mL	20.3455 mL	101.7273 mL
5 mM	0.4069 mL	2.0345 mL	4.0691 mL	20.3455 mL
10 mM	0.2035 mL	1.0173 mL	2.0345 mL	10.1727 mL
20 mM	0.1017 mL	0.5086 mL	1.0173 mL	5.0864 mL
50 mM	0.0407 mL	0.2035 mL	0.4069 mL	2.0345 mL
100 mM	0.0203 mL	0.1017 mL	0.2035 mL	1.0173 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc