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Xanthine oxidase-IN-10
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Catalog No. T78984Cas No. 851429-65-7
Alias XO8 analog
Xanthine oxidase-IN-10 (XO8 analog) is an inhibitor of xanthine oxidase (XO) used in gout research.
Xanthine oxidase-IN-10
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Purity: 99.16%
Catalog No. T78984Alias XO8 analogCas No. 851429-65-7
Xanthine oxidase-IN-10 (XO8 analog) is an inhibitor of xanthine oxidase (XO) used in gout research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $117 | In Stock | In Stock | |
| 5 mg | $290 | In Stock | In Stock | |
| 10 mg | $415 | In Stock | In Stock | |
| 25 mg | $648 | In Stock | In Stock | |
| 50 mg | $893 | In Stock | In Stock | |
| 100 mg | $1,180 | - | In Stock | |
| 200 mg | $1,590 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.16%
Appearance:Solid
Color:White
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Product Introduction
Xanthine oxidase-IN-10 AI Summary
Xanthine oxidase-IN-10 inhibits MCP1-induced chemotaxis in mouse RAW264.7 cells at 25 μg/mL, showing a 10.1% inhibition relative to the control. Additionally, it has demonstrated antibacterial activity against Escherichia coli after 24 hours using the agar diffusion technique, with an inhibition zone of 15.0 mm. Furthermore, Xanthine oxidase-IN-10 exhibits bioactivity by displacing [3H]rosiglitazone from the recombinant human C-terminal His-tagged MitoNEET cytosolic domain, with an IC50 value of 37,320,000 nM and a Ki value of 1,594,000 nM, indicating its potential interaction with this target..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Xanthine oxidase-IN-10 (XO8 analog) is an inhibitor of xanthine oxidase (XO) used in gout research. |
| Synonyms | XO8 analog |
| Molecular Weight | 204.25 |
| Formula | C10H8N2OS |
| Cas No. | 851429-65-7 |
| Smiles | C(=C\1/C(=O)N=C(N)S1)\C2=CC=CC=C2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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