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CXD101

Name: CXD101
Brand: TargetMol
SKU: T5347
Price: 54 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5347Cas No. 934828-12-3

Alias CXD-101

CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II

CXD101

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Purity: 99.82%

Catalog No. T5347Alias CXD-101Cas No. 934828-12-3

CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II

Pack Size	Price	Availability
1 mg	$54	In Stock
5 mg	$126	In Stock
10 mg	$198	In Stock
25 mg	$405	In Stock
50 mg	$597	In Stock
100 mg	$852	In Stock
1 mL x 10 mM (in DMSO)	$126	In Stock

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Purity:99.82%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II
Targets&IC50	HDAC3:550 nM , HDAC2:570 nM, HDAC1:63 nM
Synonyms	CXD-101

Chemical Properties

Molecular Weight	403.52
Formula	C₂₄H₂₉N₅O
Cas No.	934828-12-3
Smiles	Cc1nn(C)cc1CN1CCC(CC1)c1ccc(cc1)C(=O)Nc1ccccc1N
Relative Density.	1.23 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 31 mg/mL (76.82 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4782 mL	12.3910 mL	24.7819 mL	123.9096 mL
5 mM	0.4956 mL	2.4782 mL	4.9564 mL	24.7819 mL
10 mM	0.2478 mL	1.2391 mL	2.4782 mL	12.3910 mL
20 mM	0.1239 mL	0.6195 mL	1.2391 mL	6.1955 mL
50 mM	0.0496 mL	0.2478 mL	0.4956 mL	2.4782 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc