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Faltan

Name: Faltan
Brand: TargetMol
SKU: T5872
Rating: 4.5 (1 reviews)

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Catalog No. T5872Cas No. 133-07-3

Alias Folpet

Faltan (Folpet),a widely used dicarboximide fungicide,induces tumors in the mouse gastrointestinal tract,primarily in the duodenum,and is also cytotoxic effect on human bronchial epithelial cells.

Faltan

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Purity: 98.35%

Catalog No. T5872Alias FolpetCas No. 133-07-3

Faltan (Folpet),a widely used dicarboximide fungicide,induces tumors in the mouse gastrointestinal tract,primarily in the duodenum,and is also cytotoxic effect on human bronchial epithelial cells.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$40	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.35%

Appearance:Solid

Color:White to Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Faltan (Folpet),a widely used dicarboximide fungicide,induces tumors in the mouse gastrointestinal tract,primarily in the duodenum,and is also cytotoxic effect on human bronchial epithelial cells.
In vitro	Folpan 80WG particles result in a rapid cytotoxic effect on human bronchial epithelial cells in vitro that could be in part explained by oxidative stress, characterised by membrane lipid peroxidation and ROS production[1].
Cell Research	Sub-confluent 16HBE14o- plated on collagen-coated 60 mm dishes were exposed to Folpan 80WG particles corresponding to 0, 1.85 and 3.70 g/cm^2 folpet (0, 10 and 20 μM) for 2, 4 and 24 h in RPMI-1640 medium w/o phenol red , w/o FCS, supplemented with 1% l-glutamine (200 mM), 1% penicillin (10^4 U/ml), 1% streptomycin (10 mg/ml) and 1% fungizone (25 μg/ml)[1].
Synonyms	Folpet

Chemical Properties

Molecular Weight	296.56
Formula	C₉H₄Cl₃NO₂S
Cas No.	133-07-3
Smiles	ClC(Cl)(Cl)SN1C(=O)c2ccccc2C1=O
Relative Density.	1.5097 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (421.5 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 5 mg/mL (16.86 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3720 mL	16.8600 mL	33.7200 mL	168.5999 mL
5 mM	0.6744 mL	3.3720 mL	6.7440 mL	33.7200 mL
10 mM	0.3372 mL	1.6860 mL	3.3720 mL	16.8600 mL
20 mM	0.1686 mL	0.8430 mL	1.6860 mL	8.4300 mL
50 mM	0.0674 mL	0.3372 mL	0.6744 mL	3.3720 mL
100 mM	0.0337 mL	0.1686 mL	0.3372 mL	1.6860 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc