store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmission.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 478.00 | |
5 mg | In stock | $ 1,180.00 | |
10 mg | In stock | $ 1,580.00 | |
25 mg | In stock | $ 2,350.00 | |
50 mg | In stock | $ 3,180.00 |
Description | Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmission. |
In vivo | As compared with placebo, VX-548 at the highest dose (a 100-mg oral loading dose of VX-548, followed by a 50-mg maintenance dose every 12 hours), but not at lower doses (a 20-mg loading dose, followed by a 10-mg maintenance dose every 12 hours), reduced acute pain over a period of 48 hours after abdominoplasty or bunionectomy.[1] |
Synonyms | VX-548 |
Molecular Weight | 473.39 |
Formula | C21H20F5N3O4 |
CAS No. | 2649467-58-1 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (211.24 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Suzetrigine 2649467-58-1 Membrane transporter/Ion channel Sodium Channel VX-548 VX 548 VX548 inhibitor inhibit