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ML-262 (Synonyms: ML262)

Name: ML-262
Brand: TargetMol
SKU: T35801
Rating: 4.5 (1 reviews)

Catalog No. T35801 Copy Product Info

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ML-262 is an effective inhibitor of hepatic lipid droplet formation and is used in studies of non-alcoholic fatty liver disease.

ML-262

Copy Product Info

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Catalog No. T35801

Synonyms ML262

ML-262 is an effective inhibitor of hepatic lipid droplet formation and is used in studies of non-alcoholic fatty liver disease.

Cas No. 902502-82-3

Pack Size	Price	USA Stock	Global Stock
1 mg	$159	35 days	35 days
5 mg	$686	35 days	35 days
10 mg	$1,230	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	ML-262 is an effective inhibitor of hepatic lipid droplet formation and is used in studies of non-alcoholic fatty liver disease.
In vitro	ML-262 is a species-specific inhibitor of liver lipid droplet formation (IC50=6.4 nM in mouse AML-12 hepatocytes). [1]
Synonyms	ML262

Chemical Properties

Molecular Weight	480.62
Formula	C₂₇H₃₂N₂O₄S
Cas No.	902502-82-3
Smiles	O=C(NCCC1=CC=C(OCC)C(OCC)=C1)C=2SC(=C(C2)C=3C=CC=CC3)N4CCOCC4
Relative Density.	1.183 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 8 mg/mL (16.65 mM), Sonication is recommended.

DMF: 8 mg/mL (16.65 mM), Sonication is recommended.

Solution Preparation Table

DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.0806 mL	10.4032 mL	20.8065 mL	104.0323 mL
5 mM	0.4161 mL	2.0806 mL	4.1613 mL	20.8065 mL
10 mM	0.2081 mL	1.0403 mL	2.0806 mL	10.4032 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc