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7-Dehydrocholesterol

🥰Excellent
Catalog No. T4923Cas No. 434-16-2
Alias Provitamin D3, 7-DHC

7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.

7-Dehydrocholesterol

7-Dehydrocholesterol

🥰Excellent
Purity: 99.23%
Catalog No. T4923Alias Provitamin D3, 7-DHCCas No. 434-16-2
7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$33In StockIn Stock
100 mg$47In StockIn Stock
500 mg$112In StockIn Stock
1 mL x 10 mM (in DMSO)$39In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.23%
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Product Introduction

Bioactivity
Description
7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
In vitro
7-Dehydrocholesterol, a biosynthetic precursor of cholesterol and vitamin D3, is found in high concentrations in the skin. Upon UV irradiation, it converts to pre-vitamin D3 and is also exposed to exogenous radical sources and oxygen.
SynonymsProvitamin D3, 7-DHC
Chemical Properties
Molecular Weight384.64
FormulaC27H44O
Cas No.434-16-2
SmilesCC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Relative Density.1 g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 11 mg/mL (28.6 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5998 mL12.9992 mL25.9983 mL129.9917 mL
5 mM0.5200 mL2.5998 mL5.1997 mL25.9983 mL
10 mM0.2600 mL1.2999 mL2.5998 mL12.9992 mL
20 mM0.1300 mL0.6500 mL1.2999 mL6.4996 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

InhibitorinhibitHuman Endogenous MetaboliteEndogenousMetaboliteEndogenous Metabolite7-Dehydrocholesterol7Dehydrocholesterol7 Dehydrocholesterol
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