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CM-352

Name: CM-352
Brand: TargetMol
SKU: T70470
Price: 416 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T70470Cas No. 1542205-83-3

CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.

CM-352

🥰Excellent

Purity: 99.36%

Catalog No. T70470Cas No. 1542205-83-3

CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.

Pack Size	Price	Availability
1 mg	$416	In Stock
5 mg	$882	In Stock
10 mg	$1,080	In Stock
25 mg	$1,420	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.36%

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COA HNMR LCMS ORP

Product Introduction

Bioactivity

Description	CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.
Targets&IC50	MMP3:15 nM, MMP10:12 nM

Chemical Properties

Molecular Weight	487.57
Formula	C₂₄H₂₉N₃O₆S
Cas No.	1542205-83-3
Smiles	S(=O)(=O)([C@@]1(C(NO)=O)CC2(CC1)CCNCC2)C3=CC=C(OC4=CC=C(C(NC)=O)C=C4)C=C3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 18.33 mg/mL (37.6 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0510 mL	10.2549 mL	20.5099 mL	102.5494 mL
5 mM	0.4102 mL	2.0510 mL	4.1020 mL	20.5099 mL
10 mM	0.2051 mL	1.0255 mL	2.0510 mL	10.2549 mL
20 mM	0.1025 mL	0.5127 mL	1.0255 mL	5.1275 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc