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Memantine hydrochloride

Name: Memantine hydrochloride
Brand: TargetMol
SKU: T1443
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1443Cas No. 41100-52-1

Alias Namenda, Memantine HCl, D-145 (hydrochloride)

Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.

Memantine hydrochloride

🥰Excellent

Purity: 99.96%

Catalog No. T1443Alias Namenda, Memantine HCl, D-145 (hydrochloride)Cas No. 41100-52-1

Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.

Pack Size	Price	Availability
200 mg	$42	In Stock
500 mg	$50	In Stock
1 g	$63	In Stock

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Purity:99.96%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.
Targets&IC50	CYP2B6:0.51 nM(Ki), CYP2D6:94.9 μM(Ki)
Synonyms	Namenda, Memantine HCl, D-145 (hydrochloride)

Chemical Properties

Molecular Weight	215.76
Formula	C₁₂H₂₂ClN
Cas No.	41100-52-1
Smiles	Cl.[H][C@]12C[C@]3(C)C[C@](C)(C1)C[C@](N)(C2)C3
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50.00 mg/mL (231.74 mM), Sonication is recommended.

H2O: 28.00 mg/mL (129.77 mM), Sonication is recommended.

Ethanol: 40.00 mg/mL (185.39 mM), Sonication is recommended.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.6348 mL	23.1739 mL	46.3478 mL	231.7390 mL
5 mM	0.9270 mL	4.6348 mL	9.2696 mL	46.3478 mL
10 mM	0.4635 mL	2.3174 mL	4.6348 mL	23.1739 mL
20 mM	0.2317 mL	1.1587 mL	2.3174 mL	11.5869 mL
50 mM	0.0927 mL	0.4635 mL	0.9270 mL	4.6348 mL
100 mM	0.0463 mL	0.2317 mL	0.4635 mL	2.3174 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc