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Ceftaroline fosamil

Name: Ceftaroline fosamil
Brand: TargetMol
SKU: T7387
Price: 54 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T7387Cas No. 400827-46-5

Alias TAK-599, PPI0903

Ceftaroline fosamil (TAK-599) is a cephalosporin, with activity against Gram-positive pathogens.

Ceftaroline fosamil

🥰Excellent

Purity: 97.09%

Catalog No. T7387Alias TAK-599, PPI0903Cas No. 400827-46-5

Ceftaroline fosamil (TAK-599) is a cephalosporin, with activity against Gram-positive pathogens.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$54	In Stock	In Stock
5 mg	$128	In Stock	In Stock
10 mg	$213	-	In Stock
25 mg	$397	-	In Stock
50 mg	$622	-	In Stock
100 mg	$885	-	In Stock
1 mL x 10 mM (in DMSO)	$215	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.09%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Ceftaroline fosamil (TAK-599) is a cephalosporin, with activity against Gram-positive pathogens.
In vivo	Ceftaroline fosamil 600 mg given every 12 h was superior to ceftriaxone 2 g given every 24 h for the treatment of Asian patients with PORT III-IV community-acquired pneumonia. These data suggest that ceftaroline fosamil should be regarded as an alternative to ceftriaxone in empirical treatment regimens for this patient population.
Synonyms	TAK-599, PPI0903

Chemical Properties

Molecular Weight	744.74
Formula	C₂₄H₂₅N₈O₁₀PS₄
Cas No.	400827-46-5
Smiles	CCON=C(C1=NSC(=N1)NP(=O)(O)O)C(=O)NC2C3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C=C5)C)C(=O)O.CC(=O)[O-]
Relative Density.	no data available
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 14 mg/mL (32.22 mM), Sonication and heating are recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (2.69 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3428 mL	6.7138 mL	13.4275 mL	67.1375 mL
5 mM	0.2686 mL	1.3428 mL	2.6855 mL	13.4275 mL
10 mM	0.1343 mL	0.6714 mL	1.3428 mL	6.7138 mL
20 mM	0.0671 mL	0.3357 mL	0.6714 mL	3.3569 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc