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REVERSE T3
🥰Excellent
Catalog No. T7578Cas No. 5817-39-0
Alias 3,3',5'-triiodo-L-thyronine
Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.
REVERSE T3
🥰Excellent
Purity: 97.89%
Catalog No. T7578Alias 3,3',5'-triiodo-L-thyronineCas No. 5817-39-0
Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $42 | In Stock | |
| 2 mg | $58 | In Stock | |
| 5 mg | $83 | In Stock | |
| 10 mg | $156 | In Stock | |
| 25 mg | $297 | In Stock | |
| 50 mg | $463 | In Stock | |
| 100 mg | $668 | In Stock |
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Purity:97.89%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes. |
| In vitro | Reverse T3(T3) pre-conditioning leads to beneficial effects in the liver of brain-dead rats as seen by lower cellular injury and reduced apoptosis, and supports the suggested role of reverse T3(T3) hormone therapy in the management of brain-dead donors[1]. |
| Cell Research | Brain death (BD) was induced in mechanically ventilated rats by inflation of a Fogarty catheter in the epidural space.?T3 (0.1 mg/kg) or vehicle was administered intraperitoneally 2 h prior to BD induction.?After 4 h of BD, serum and liver tissue were collected.?RT-qPCR, routine biochemistry, and immunohistochemistry were performed[1]. |
| Synonyms | 3,3',5'-triiodo-L-thyronine |
| Molecular Weight | 650.97 |
| Formula | C15H12I3NO4 |
| Cas No. | 5817-39-0 |
| Smiles | N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C=C1)C(O)=O |
| Relative Density. | 2.387 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: < 1.63 mg/mL, Sonication is recommended.  |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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