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RBC6

Name: RBC6
Brand: TargetMol
SKU: T24707
Price: 55 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: RBC-6, RBC 6) Copy Product Info

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Synonyms: RBC-6, RBC 6

Catalog No. T24707 Copy Product Info

Purity: 99.17%

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RBC6 is a small-molecule inhibitor that targets the Ras-like GTPase Ral. RBC6 blocks the interaction between Ral and its downstream effector protein RALBP1, thereby disrupting Ral-mediated cellular signaling. RBC6 inhibits Ral-dependent cell migration in mouse embryonic fibroblasts, as well as anchorage-independent growth in various human cancer cell lines.

Cas No. 381186-64-7

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Pack Size	Price	USA Stock	Global Stock
1 mg	$55	-	In Stock
5 mg	$129	-	In Stock
10 mg	$213	-	In Stock
25 mg	$428	-	In Stock
50 mg	$687	-	In Stock
100 mg	$1,090	-	In Stock
1 mL x 10 mM (in DMSO)	$143	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.17%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	RBC6 is a small-molecule inhibitor that targets the Ras-like GTPase Ral. RBC6 blocks the interaction between Ral and its downstream effector protein RALBP1, thereby disrupting Ral-mediated cellular signaling. RBC6 inhibits Ral-dependent cell migration in mouse embryonic fibroblasts, as well as anchorage-independent growth in various human cancer cell lines.
Synonyms	RBC-6, RBC 6

Chemical Properties

Molecular Weight	365.21
Formula	C₁₆H₁₄Cl₂N₄O₂
Cas No.	381186-64-7
Smiles	N#CC1=C(OC=2NN=C(C2C1C=3C=C(Cl)C=C(Cl)C3O)CCC)N
Relative Density.	1.56 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (109.53 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7382 mL	13.6908 mL	27.3815 mL	136.9075 mL
5 mM	0.5476 mL	2.7382 mL	5.4763 mL	27.3815 mL
10 mM	0.2738 mL	1.3691 mL	2.7382 mL	13.6908 mL
20 mM	0.1369 mL	0.6845 mL	1.3691 mL	6.8454 mL
50 mM	0.0548 mL	0.2738 mL	0.5476 mL	2.7382 mL
100 mM	0.0274 mL	0.1369 mL	0.2738 mL	1.3691 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.