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ML281

Name: ML281
Brand: TargetMol
SKU: T3423
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3423Cas No. 1404437-62-2

ML281, a potent and selective STK33 inhibitor, exhibits an IC50 of 14 nM.

ML281

🥰Excellent

Purity: 99.87%

Catalog No. T3423Cas No. 1404437-62-2

ML281, a potent and selective STK33 inhibitor, exhibits an IC50 of 14 nM.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$30	In Stock	In Stock
5 mg	$73	In Stock	In Stock
10 mg	$98	In Stock	In Stock
25 mg	$198	In Stock	In Stock
50 mg	$328	In Stock	In Stock
100 mg	$526	-	In Stock
500 mg	$1,150	-	In Stock
1 mL x 10 mM (in DMSO)	$80	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.87%

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description	ML281, a potent and selective STK33 inhibitor, exhibits an IC50 of 14 nM.
Targets&IC50	STK33:14 nM.

Chemical Properties

Molecular Weight	389.47
Formula	C₂₂H₁₉N₃O₂S
Cas No.	1404437-62-2
Smiles	CC(C)c1ccc(NC(=O)c2cccs2)c(c1)-c1nc2ccccc2[nH]c1=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (128.38 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5676 mL	12.8380 mL	25.6759 mL	128.3796 mL
5 mM	0.5135 mL	2.5676 mL	5.1352 mL	25.6759 mL
10 mM	0.2568 mL	1.2838 mL	2.5676 mL	12.8380 mL
20 mM	0.1284 mL	0.6419 mL	1.2838 mL	6.4190 mL
50 mM	0.0514 mL	0.2568 mL	0.5135 mL	2.5676 mL
100 mM	0.0257 mL	0.1284 mL	0.2568 mL	1.2838 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc