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S-Gboxin

Name: S-Gboxin
Brand: TargetMol
SKU: T5335
Price: 97 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5335Cas No. 2101317-21-7

S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits the growth of mouse and human glioblastoma (GBM, IC50: 470 nM).

S-Gboxin

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Purity: 99.32%

Catalog No. T5335Cas No. 2101317-21-7

S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits the growth of mouse and human glioblastoma (GBM, IC50: 470 nM).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$97	In Stock	In Stock
2 mg	$142	In Stock	In Stock
5 mg	$239	In Stock	In Stock
10 mg	$347	In Stock	In Stock
25 mg	$589	In Stock	In Stock
50 mg	$816	In Stock	In Stock
100 mg	$1,070	In Stock	In Stock
200 mg	$1,450	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$316	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.32%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits the growth of mouse and human glioblastoma (GBM, IC50: 470 nM).
Targets&IC50	GBM:470 nM

Chemical Properties

Molecular Weight	600.46
Formula	C₂₇H₃₂F₃IN₂O₂
Cas No.	2101317-21-7
Smiles	[I-].CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)C[n+]1c(-c2cccc(c2)C(F)(F)F)n(C)c2ccccc12
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 85 mg/mL (141.56 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 8 mg/mL (13.32 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6654 mL	8.3269 mL	16.6539 mL	83.2695 mL
5 mM	0.3331 mL	1.6654 mL	3.3308 mL	16.6539 mL
10 mM	0.1665 mL	0.8327 mL	1.6654 mL	8.3269 mL
20 mM	0.0833 mL	0.4163 mL	0.8327 mL	4.1635 mL
50 mM	0.0333 mL	0.1665 mL	0.3331 mL	1.6654 mL
100 mM	0.0167 mL	0.0833 mL	0.1665 mL	0.8327 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc